An example: NGS

First the sample is entered in our proprietary database. Then a barcode is attached to the patient’s blood or bone marrow and finally forwarded for cell lysis. This involves determining the number of isolated mononuclear cells at various measuring times for further molecular analyses. Afterwards, robots divide the samples into equal portions and place them in vials labelled with a 2-D barcode. These vials are automatically frozen in large refrigerator units at –80°C, i.e. –20°C. The freezing robot automatically retrieves these vials for further analyses in 96-well plate format the next morning. Other machines prepare the DNA, i.e. RNA. Once this stage is complete, another set of devices prepare the samples for next-generation sequencing machines – again in 96-well plate format with barcode monitoring. Once the NGS devices have completed sequencing, the information on the patient case is sent back to the proprietary database, where it is prepared for final diagnostics using a large number of specific algorithms, including artificial intelligence technologies. The medical technicians, molecular biologists and bioinformatics specialists involved in the process take care of diagnostics and shipping, with validation by hematologists.