Blood and bone marrow samples are received in the sample receipt area. They are unpacked, entered into our system and identified with an internal barcode. From here on, each sample is allocated to a certain employee and equipment and is traceable in real time.

Immunophenotyping is key to the diagnostic work-up of hematologic neoplasias. It is used to corroborate diagnosis, classify diseases, assess prognoses and to quantify malignant cells over the course of treatment (minimal/measurable residual disease, MRD). Diagnostic application of the method is based on the characterization of antigen expression patterns of malignant cells and their discrimination from healthy cells.

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Molecular genetics employs state-of-the-art methods for the identification of gene mutations with the highest sensitivity. Key areas of molecular genetics are the elucidation of genetic tumor profiles and determination of minimal residual disease (MRD).

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The diagnostic work-up of hematological neoplasias is based on cytomorphology of blood and bone marrow smears. It is used to corroborate the diagnosis, classify diseases and assess prognoses over the course of treatment. In this regard, cytomorphology mainly involves the assessment of panoptical stains and a variety of cytohistochemical stains of blood and bone marrow smears.

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Chromosome analysis is now considered an obligatory testing method for the diagnosis of hematological neoplasias. Its findings contribute to substantiating the diagnosis, although the prognostic significance that can be confirmed from the karyotype of malignant cells is far more important. Cancer-associated chromosomal aberrations occur only in malignant cells. These are acquired genetic mutations. Hence, the other cells in the body of a patient suffering from a hematological neoplasias are cytogenetically normal.

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Fluorescence in situ hybridization (FISH) uses fluorescent probes for the identification of known chromosomal or, rather, genetic aberrations in metaphase chromosomes and interphase nuclei.

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In the newly designed Worklab, visiting scientists from all over the world are working on research projects in the field of leukemia diagnostics.

The spacious and bright lobby offers space for receptions and events of all kinds. On both sides of the foyer, there are two smaller conference rooms with 9 and 11 seats, respectively. On the front side, you get access to two seminar rooms, which can be joined together by a sliding wall to form a large conference room. The lobby hosts a large number of screens ready to play any combination of content.

The "large classroom" can accommodate up to 190 people and is one of the largest video conference rooms in Germany. Equipped with the latest technology such as a 6.70x1.71m LED wall, a number of cameras, and an integrated sound and loudspeaker system, this room meets MLL's high standards. The innovative microphone system that is integrated in the ceiling enables the speaker to talk without lavalier microphones or hand-held transmitters and still be heard well everywhere in the room. In addition, an interaction with the audience can take place without hand microphones having to be passed around.

A movable partitioning wall subdivides the "large classroom" into two separate rooms (the "seminar room" and the "small classroom"). The "seminar room" can accommodate 56 persons, and the "small classroom" 98 persons.

The seminar room has a 2.44 x 1.37 m LED wall. Microphones, ceiling loudspeakers and cameras make this room ideal for video conferences. The "seminar room" accommodates 56 persons.

Both conference rooms are elegant with dark accents. They are ideal for meetings and discussions that can be attended by up to 11 people. Both rooms can be dimmed using tinted Smart-Glass windows protecting them from the gaze of by-passers. A large LED screen, a camera and an integrated microphone and speaker system make these rooms ideally suited for video conferences.

Unlike conference rooms 1 and 2 with dark accents, conference room 3 features the MLL colors red and grey. A large window lets in ample light. In addition, the room is equipped with an integrated kitchen for event catering.

All rooms are equipped with the latest and most intuitive technology. Alongside the screens, the cameras and the built-in microphone and loudspeaker systems, each room is equipped with an iPad which can be used to control the light, the roller blinds and glass walls. A digital flipchart allows for paperless work and can send the notes to participants by e-mail upon request.